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KMID : 0371219920140010190
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Medical Bulletin of the Presbyterian Medical Center
1992 Volume.14 No. 1 p.190 ~ p.196
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T Lymphocyte subsets, B Lympholcyte and NK Cell Activity in Cervical Intraepithelial neoplasia and Cervical Cancer Patients
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이승철
장종호/김관수/이형렬
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Abstract
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Various reports suggest that most tumors in human may develop when their cellular immune system is depressed.
Distribution of T-lymphocyte subsets, B-lymphocyte & natural killer cell(NK) activity were examined in 14 patients with cervical intraepithelial neoplasia(CIN), 26 cervical cancer patients, and 16 normal controls.
@ES The results were as follows:
@EN 1. Percentage of T-cell among lymphocyte was 77.82±8.17% in the CIN patients, 79.09±5.19% in the cervical cancer patients and 77.78±4.69% in the normal controls.
There was no significant difference.
2. Percentage of B cell among lymphcyte was 11.85±6.6% in the CIN patients, 11.55±5.23% in the cervical cancer patients and 11.54±4.21% in the normal controls.
The was no significant difference.
3. Percentage of Null cell among lympholcyte was 10.31±4.57% in the CIN patients, 9.73±3.92% in the cervical cancer patients and 10.68±3.65% in the controls.
The was no significant difference.
4. T4:T8 ratio was 2.19±1.12 in the CIN patients, 2.22±0.83% cervical cancer patients and 1.96±0.82 in the controls.
There was no significant difference.
5. NK cell activity were 24.98±16.62 in the CIN patients 23.7±12.66% in the cervical cancer patients and 37.52±14.01% in the normal controls.
There was significant decrease in the CIN patients & cervical cancer patients compared to the normal controls.
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